{"id":1865,"date":"2017-05-24T20:45:51","date_gmt":"2017-05-24T20:45:51","guid":{"rendered":"https:\/\/www.primarycaregenetics.org\/?page_id=1865"},"modified":"2017-05-24T20:45:51","modified_gmt":"2017-05-24T20:45:51","slug":"breast-and-ovarian-cancer","status":"publish","type":"page","link":"https:\/\/www.primarycaregenetics.org\/?page_id=1865&lang=en","title":{"rendered":"Breast and ovarian cancer"},"content":{"rendered":"<p><strong>Patients with a family history of breast and\/or ovarian cancer &#8211; who should you refer? <\/strong><\/p>\n<p><strong>NICE Guidelines <\/strong><\/p>\n<p><a href=\"https:\/\/www.nice.org.uk\/guidance\/cg164\/chapter\/Recommendations#clinical-significance-of-a-family-history-of-breast-cancer\"><strong>https:\/\/www.nice.org.uk\/guidance\/cg164\/chapter\/Recommendations#clinical-significance-of-a-family-history-of-breast-cancer<\/strong><\/a><\/p>\n<p><strong>Summary of points 1.3.3. and 1.3.4 of the guidelines <\/strong><\/p>\n<p><strong>Referral from primary care<\/strong><\/p>\n<p>1.3.3<\/p>\n<p>People without a personal history of breast cancer who meet the following criteria should be offered referral to secondary care:<\/p>\n<ul>\n<li>one first-degree female relative diagnosed with breast cancer at younger than age 40&nbsp;years&nbsp;<strong>or<\/strong><\/li>\n<li>one first-degree male relative diagnosed with breast cancer at any age&nbsp;<strong>or<\/strong><\/li>\n<li>one first-degree relative with bilateral breast cancer where the first primary was diagnosed at younger than age 50&nbsp;years&nbsp;<strong>or<\/strong><\/li>\n<li>two first-degree relatives, or one first-degree and one second-degree relative, diagnosed with breast cancer at any age&nbsp;<strong>or<\/strong><\/li>\n<li>one first-degree or second-degree relative diagnosed with breast cancer at any age and one first-degree or second-degree relative diagnosed with ovarian cancer at any age (one of these should be a first-degree relative)&nbsp;<strong>or<\/strong><\/li>\n<li>three first-degree or second-degree relatives diagnosed with breast cancer at any age.&nbsp;<strong>[2004]<\/strong><\/li>\n<\/ul>\n<p>1.3.4<\/p>\n<p>Advice should be sought from the designated secondary care contact if any of the following are present in the family history in addition to breast cancers in relatives not fulfilling the above criteria:<\/p>\n<ul>\n<li>bilateral breast cancer<\/li>\n<li>male breast cancer<\/li>\n<li>ovarian cancer<\/li>\n<li>Jewish ancestry<\/li>\n<li>sarcoma in a relative younger than age 45&nbsp;years<\/li>\n<li>glioma or childhood adrenal cortical carcinomas<\/li>\n<li>complicated patterns of multiple cancers at a young age<\/li>\n<li>paternal history of breast cancer (two or more relatives on the father&#8217;s side of the family).&nbsp;<strong>[2004]<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Patients with a family history of breast and\/or ovarian cancer &#8211; who should you refer? NICE Guidelines https:\/\/www.nice.org.uk\/guidance\/cg164\/chapter\/Recommendations#clinical-significance-of-a-family-history-of-breast-cancer Summary of points 1.3.3. and 1.3.4 of the guidelines Referral from primary care 1.3.3 People without a personal history of breast cancer who meet the following criteria should be offered referral to secondary care: one first-degree female relative diagnosed with breast cancer at younger than age 40&nbsp;years&nbsp;or one first-degree male relative diagnosed with breast cancer at any age&nbsp;or one first-degree relative with [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":463,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"ngg_post_thumbnail":0},"_links":{"self":[{"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/pages\/1865"}],"collection":[{"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1865"}],"version-history":[{"count":1,"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/pages\/1865\/revisions"}],"predecessor-version":[{"id":1866,"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/pages\/1865\/revisions\/1866"}],"up":[{"embeddable":true,"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=\/wp\/v2\/pages\/463"}],"wp:attachment":[{"href":"https:\/\/www.primarycaregenetics.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}